This toolkit is broken into two parts. The first section highlights ten guiding principles for conducting cannabis education with young people. In this section, the concepts and values important to the delivery and implementation of cannabis education for youth are discussed. Although outlined in the context of cannabis, these principles are also applicable to education on other substances. The second section focuses on content that merits inclusion in a comprehensive cannabis education curriculum for young people, including evidence-based information about cannabis, its use and effects, as well as harm reduction strategies. This section also addresses many common claims made about youth cannabis use, such as the impacts on the developing brain.