This project was managed by Addictions and Mental Health Ontario (AMHO), with funding from Health Canada’s Substance Use and Addictions Program (SUAP). The project was supported by an expert Advisory Committee comprised of a broad range of experts, including individuals with lived/living experience, health system planners, and representatives from public health, addiction treatment services and other relevant sectors, as well as other key stakeholders in Ontario. The project also built upon the work of the Canadian Research Institute in Substance Misuse (CRISM), which has been focused on facilitating and supporting the successful delivery of injectable Opioid Agonist Treatment (iOAT) in Canada.